{"id":20102,"date":"2026-04-06T12:44:51","date_gmt":"2026-04-06T11:44:51","guid":{"rendered":"https:\/\/cabd.es\/investigation\/departments\/cell-biology-and-biotechnology\/"},"modified":"2026-08-11T11:37:18","modified_gmt":"2026-08-11T10:37:18","slug":"organismal-dynamics","status":"publish","type":"page","link":"https:\/\/cabd.es\/en\/investigation\/departments\/organismal-dynamics\/","title":{"rendered":"Organismal Dynamics"},"content":{"rendered":"

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Departments<\/p>\n

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Organismal Dynamics<\/h1>\n

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Department Presentation<\/h2>\n

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Developmental processes often operate beyond the level of individual cells or tissues, shaping the organism as an integrated whole and coordinating the function of its components and organs. The Organismal Dynamics Department investigates how gene regulation, internal cues, and a changing external environment influence how animals develop, adapt, and function as complete systems. Using a diverse set of experimental models\u2014including yeast, primary cell lines, worms, flies, fish, and mice\u2014our research spans scales from sub\u2011cellular architecture to organism\u2011level physiology. We explore the structure and function of key cellular components such as the nucleus, mitochondria, and proteasome, as well as phenomena including bioenergetics, muscle development, hormonal effects and inter-organ communication. Through this integrative approach, we aim to uncover how these molecular and physiological mechanisms shape phenomena that extend beyond organ development, including diseases, neurodegeneration, longevity, reproduction, and whole\u2011body homeostasis.<\/p>\n<\/div>\n

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Research Groups<\/h2>\n

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Coenzyme Q synthesis in Saccharomyces cerevisae and its implication in the mitochondrial health. lifespan and ageing<\/a><\/p>\n

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Molecular embryology<\/a><\/p>\n

\u00a0<\/p>\n

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Genetic regulation of ageing in Caenorhabditis elegans<\/a><\/p>\n

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Mitochondrial signalling crosstalk in the regulation of ageing<\/a><\/p>\n

\u00a0<\/p>\n

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Nuclear Dynamics in Cell and Developmental Biology<\/a><\/p>\n

\u00a0<\/p>\n

[\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_team_member name=”Dr Rafael Rodr\u00edguez Daga” position=”Principal Investigator” image_url=”https:\/\/cabd.es\/wp-content\/uploads\/2026\/03\/18.jpg” _builder_version=”4.27.6″ _module_preset=”eedb4f0b-945a-4987-9b31-1de9f0639f80″ header_level=”h3″ header_text_align=”center” vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ text_orientation=”center” link_option_url=”https:\/\/cabd.es\/en\/investigation\/departments\/organismal-dynamics\/dr-rafael-rodriguez-daga\/” z_index_tablet=”0″ custom_css_free_form=” selector h3::before {|| content: %22%22;|| display: inline-block;|| position: relative;|| top: calc(-.1 * 1em);|| vertical-align: middle;|| height: calc(4px + .7em);|| margin-right: calc(5px + .2em);|| border-left: calc(5px + .1em) solid #e47e59;||}||||selector .et_pb_team_member_image {|| width: 250px; \/* O cualquier tama\u00f1o *\/|| height: 250px; \/* Mismo valor que el ancho *\/|| border-radius: 50%;|| box-shadow: 0 10px 25px rgba(0, 0, 0, .1);||}||||||||||” custom_css_member_image=” margin-left: auto;|| margin-right: auto;||||||” header_text_shadow_horizontal_length_tablet=”0px” header_text_shadow_vertical_length_tablet=”0px” header_text_shadow_blur_strength_tablet=”1px” body_text_shadow_horizontal_length_tablet=”0px” body_text_shadow_vertical_length_tablet=”0px” body_text_shadow_blur_strength_tablet=”1px” position_text_shadow_horizontal_length_tablet=”0px” position_text_shadow_vertical_length_tablet=”0px” position_text_shadow_blur_strength_tablet=”1px” body_link_text_shadow_horizontal_length_tablet=”0px” body_link_text_shadow_vertical_length_tablet=”0px” body_link_text_shadow_blur_strength_tablet=”1px” body_ul_text_shadow_horizontal_length_tablet=”0px” body_ul_text_shadow_vertical_length_tablet=”0px” body_ul_text_shadow_blur_strength_tablet=”1px” body_ol_text_shadow_horizontal_length_tablet=”0px” body_ol_text_shadow_vertical_length_tablet=”0px” body_ol_text_shadow_blur_strength_tablet=”1px” body_quote_text_shadow_horizontal_length_tablet=”0px” body_quote_text_shadow_vertical_length_tablet=”0px” body_quote_text_shadow_blur_strength_tablet=”1px” border_radii=”on|0%|0%|0%|0%” border_radii_image=”on|50%|50%|50%|50%” border_color_all_image=”RGBA(255,255,255,0)” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” box_shadow_style_image=”preset1″ box_shadow_vertical_image_tablet=”0px” box_shadow_blur_image_tablet=”40px” text_shadow_horizontal_length_tablet=”0px” text_shadow_vertical_length_tablet=”0px” text_shadow_blur_strength_tablet=”1px” saved_tabs=”all” global_colors_info=”{}”]<\/p>\n

Nuclear Architecture and Dynamics<\/a><\/p>\n

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Regulation of skeletal muscle mass and function from development to ageing<\/a><\/p>\n

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Coordination of stem cells, physiology and behavior<\/a><\/p>\n

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The Macrophage Axis in Inter-Organ Physiology<\/a><\/p>\n

 <\/p>\n

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Gene expression and development in Coenzyme Q deficiency: a model to establish the origin of this mitochondrial disease<\/a><\/p>\n

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Molecular bases of Coenzyme Q deficiency and bioenergetics of development<\/a><\/p>\n

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Metabolism, antioxidant systems and aging<\/a><\/p>\n

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Investigating the Role of Mitochondrial Prohibitin Complex in Age-Related Neurodegeneration<\/a><\/p>\n

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Control of nuclear proteostasis<\/a><\/p>\n

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