{"id":20612,"date":"2026-04-10T10:15:08","date_gmt":"2026-04-10T09:15:08","guid":{"rendered":"https:\/\/cabd.es\/investigation\/departments\/regulacion-genica-y-morfogenesis\/dra-elena-camacho-aguilar\/"},"modified":"2026-11-03T11:48:11","modified_gmt":"2026-11-03T10:48:11","slug":"dra-elena-camacho-aguilar","status":"publish","type":"page","link":"https:\/\/cabd.es\/en\/investigation\/departments\/multicelular-dynamics\/dra-elena-camacho-aguilar\/","title":{"rendered":"Dra Elena Camacho Aguilar"},"content":{"rendered":"

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Multicellular Dynamics<\/p>\n

Sy(stem)s Developmental Biology<\/h1>\n

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Dra Elena Camacho Aguilar<\/h4>\n

Junior Group Leader Mar\u00eda de Maeztu<\/p>\n

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Summary<\/h2>\n
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During embryonic development, a single cell must generate the correct cell types in the right positions and at the right times to create a healthy human being. This is a complex and dynamic process in which cells constantly interact and interpret dynamic signals to create precise patterns. However, we still don’t fully understand how these processes are coordinated and controlled.<\/p>\n

Due to ethical and technical constraints, answering these questions\u00a0in vivo\u00a0<\/em>remains a challenge. However, recent developments in stem cell culture provide a new window into human development.<\/p>\n

With a multidisciplinary mindset, our lab leverages quantitative experimental studies with human pluripotent stem cells, bioengineering techniques, and novel approaches in mathematical modeling to study cell fate decisions and patterning processes during human development.<\/p>\n<\/div>\n

\"\"<\/p>\n

Our lab has a focus on understanding embryonic-extraembryonic tissue interactions and how they lead to and coordinate gastrulation, the state at which the three germ layers emerge and the embryo’s head-to-tail axis is defined for the first time.
If you want to know more about us, please visit our\u00a0Sy(stem)s Developmental Biology Lab website<\/a><\/strong><\/p>\n

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Five relevant publications<\/h2>\n
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Una lista m\u00e1s completa y actualizada de las publicaciones est\u00e1 disponible en:\u00a0ORCID<\/a>\u00a0o\u00a0Google Scholar<\/a>.<\/p>\n

* – Autores que contribuyeron igualmente a este trabajo.; \u2020 – Autor(es) de correspondencia<\/p>\n

– Camacho-Aguilar E\u2020, Yoon ST, Ortiz-Salazar MA, Du S, Guerra MC, Warmflash A\u2020.\u00a0Combinatorial interpretation of BMP and WNT controls the decision between primitive streak and extraembryonic fates<\/a>.\u00a0Cell Systems<\/em><\/strong>\u00a0(2024)<\/p>\n

– Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK\u2020.\u00a0Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR<\/a>.\u00a0Nature Communications<\/em>\u00a0<\/strong>(2022)<\/p>\n

– S\u00e1ez M*, Blassberg R*, Camacho-Aguilar E*, Siggia ED, Rand DA\u2020, Briscoe J\u2020.\u00a0Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions<\/a>.\u00a0Cell Systems<\/em><\/strong>\u00a0(2022)<\/p>\n

– Camacho-Aguilar E\u2020, Warmflash A, Rand DA\u2020.\u00a0Quantifying cell transitions in C. elegans with data-fitted landscape models<\/a>.\u00a0PLoS Computational Biology<\/em><\/strong>\u00a0(2021)<\/p>\n

– Camacho-Aguilar E, Warmflash A\u2020.\u00a0Insights into mammalian morphogen dynamics from embryonic stem cell systems<\/a>.\u00a0Current Topics in Developmental Biology<\/em><\/strong>\u00a0(2020)<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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Lab members & Collaborators<\/h2>\n
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Lab members<\/h3>\n

Principal Investigator<\/h4>\n

Dr. Elena Camacho Aguilar, (ecamagu\u00a0at\u00a0<\/em>upo.es)<\/p>\n

Research Assistant<\/h4>\n

Andrea Theodorou<\/p>\n

PhD Candidates<\/h4>\n

Miguel Navarro Castro (University of Seville, Co-supervised\u00a0with\u00a0Dr. M. Jos\u00e9 Jimenez<\/a>)<\/p>\n

Undergraduate Students<\/h4>\n

Pablo Mart\u00edn Berna (Undergradiate Thesis, US, Co-supervised with\u00a0Dr. M. Jos\u00e9 Jimenez<\/a>)
Gabriel Gonz\u00e1lez Parrado (Research Intern, Universidad Pablo de Olavide)<\/p>\n

Previus lab members<\/strong><\/p>\n

Irene Carrero Castro (MSc Thesis, US, Co-supervised\u00a0with\u00a0Dr. Fernando Casares<\/a>)
Grace Wang (Undergraduate Researcher, Rice University, Co-supervised\u00a0with\u00a0Dr. Aryeh Warmflash<\/a>)<\/p>\n

If you would like to know more about us, please visit our website at<\/strong>\u00a0systemsdevbiolab.com<\/a><\/p>\n

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