Coordination of stem cells, physiology and behavior

Stem cells are essential for the maintenance and renewal of our tissues by dividing through the entire life of the organisms, replacing damaged cells and maintaining the organ function. One of their key characteristics is their plasticity when responding to environmental cues and the internal state of the organism. As an example, the nutritional status of an animal can modulate the stem cell number and proliferation in many diverse tissues. However, many questions remain unanswered, as if the stem cells can in turn communicate their status and needs to the rest of the organism, and how this bidirectional communication can optimize certain body functions. An example of this is the reproduction, where gonadal stem cells produce gametes (eggs and sperm) but also physiological preparedness and triggering specific behaviors (like receptiveness and courtshipping) are required. How the internal status of the animal and the social cues affect gametogenesis? Can the status of the gonadal stem cells modulate in turn the reproductive behavior of the animal?